Boesenbergia pandurata (Roxb.) Schltr. is a tropical plant that has been used as a spice and in traditional medicine. B. pandurata contains various bioactive. This plant has 8 different botanical names which are Boesenbergia cochinchinensis (Gagnep.) Loes., Boesenbergia pandurata (Roxb.) Schltr. The medicinal plant, Boesenbergia pandurata (Roxb.) Schltr., has been reported to possess anti-oxidative and anti-inflammatory properties;.

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Helicobacter boesebbergia is a prominent Gram-negative bacteria that causes gastritis, dyspepsia, and peptic ulcer and has been linked to the development of gastric and colon cancer. It is normally cultivated at small home ranches and used as a condiment in food such as curry and soup due to its aromatic flavour, which promotes appetite.

Cell viability was determined by the MTT assay. Chemical and Pharmaceutical Bulletin. Chuakul W, Boonpleng A. Author information Article notes Copyright and License information Disclaimer. This compound also showed similar inhibitory activity towards S.

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Spoilage bacteria are another group of bacteria that cause food spoilage through fermentation and decomposition of food products. Histological analysis of healed wounds dressed with rhizomes extract showed comparatively less scar width at wound closure and healed wound contained less inflammatory cells and more collagen with angiogenesis compared to wounds dressed with vehicle pandhrata.


InYun et al. From Wikipedia, the free encyclopedia. The IC 50 value of this compound was 4. The results showed that hydrostatic pressure can be used for compound secretion into the liquid medium.

Boesenbergia rotunda – Wikipedia

Journal of Oral Science. The effect of panduratin A on boesenbergi protein expression of matriptase, prostasin, filaggrin, and caspase Although the effect of these plant extracts paled in comparison to metronidazole, a commercial antibiotic with an IC 50 value of 0. Specifically, transglutaminase catalyzes the formation of the isopeptide bond between proteins 6. The antioxidant activity of pinostrobin was proven through its ability to reduce the level of thiobarbituric acid reactive substances TBARS and through ferric reducing antioxidant power FRAP assay which gave a value of Synthesis of kavain, dihydrokavain, and analogues.


Please review our privacy policy. Drug Discovery through Bioinformatics Some bioactive compounds of B. Given the high consumption of B.

It is also used as traditional medicine to treat several illnesses, consumed as traditional tonic especially after childbirth, beauty aid for teenage girls, and as a leukorrhea preventive remedy for women.

The flowers are scarlet and bloom throughout the year in tropical countries. Thus, the mRNA and protein boesenberfia of keratinocyte differentiation markers, such as loricrin, in-volucrin, and transglutaminase were investigated to clarify the ability of BPE and panduratin A to form CE.


Boesenbergia rotunda: From Ethnomedicine to Drug Discovery

Sroisiri T, Boonyanit T. Synonyms botanical Kaempferia pandurata Roxb. Given the positive findings regarding the inhibitory activity of B. Based on Figure 4substitutions were performed individually on positions 1, 2, 3, 4, and 5 of the benzyl ring A of 4-hydroxypanduratin A and panduratin A. These reactive radicals cause direct damage to the function of normal cells. Further purification of the crude extract led to isolation of three compounds, namely, pinostrobin, alpinetin, and pinocembrin chalcone.

The Malaysian Journal of Analytical Sciences. The automated docking experiments showed that all the ligands studied did not bind to the active site of the protease, which are consistent with the bioassay results, illustrating the noncompetitive inhibitory activities for most of the ligands [ 74 ].

From Ethnomedicine to Drug Discovery”. Meanwhile, Charoensin et al.