Cardiobacterium hominis is a slow-growing, fastidious, capnophilic, Gram- negative bacillus represented by the “C” in HACEK, an acronym for. Cardiobacterium hominis is a member of the HACEK group (Haemophilus paraphrophilus, Haemophilus parainfluenzae, Aggregatibacter. Cardiobacterium hominis, a microaerophilic, pleomorphic gram-negative bacillus , is one of the AACEK organisms. C. hominis is a component of the normal flora.

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In a review of 22 cases of infective endocarditis due to C. Weiner M, Werthamer S. Influence of referral bias on the apparent clinical spectrum of infective endocarditis.

The patient was discharged home after 22 days in hospital and continued therapy with intravenous antibiotics to complete a four-week course. Cardiobacyerium Cardiovasc Surg ; Get free access to newly published articles. Adjunctive therapy is primarily valve replacement when required.

Embolism has been responsible for atypical presentations of C hominis endocarditis. Cultures of both valves were negative for bacteria, acid-fast bacilli and fungi. To these should be added a single case due to Suttonella indologenes formerly Kingella indologenes Characteristics yominis help distinguish C. J Infect Dis ; InTucker et al.

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Arch Intern Med ; Table 8 Comparison of biochemical characteristics of C. The size of the vegetations, as determined by echocardiography, was described in only four cases: Putative risk factors assessed included quality of dentition, the occurrence of recent dental work, underlying valvular disease, recent endoscopy, or surgical procedures. Francioli et al 12 described a year-old man with C hominis endocarditis who presented cardiobxcterium bacterial meningitis, thought to be secondary to septic embolization.


A review of the literature follows the case presentation.

caediobacterium Ann Biol Clin ; Rev Infect Dis ; 5: Infect Dis Rep ;5: Ruptured mycotic aneurysm of the superior mesenteric artery that was due to Cardiobacterium endocarditis. Infective endocarditis caused by slow-growing, fastidious, Gram-negative bacteria. Weiner M, Werthamer S. In many of these cases, data reporting was not complete. Previous valve replacement, previous rheumatic heart disease, previous endocarditis, known ventricular septal defect, known bicuspid aortic valve, congenital aortic valve disease type not specifiedmitral valve prolapse with murmur type not specified and dilated cardiobacterikm have all been described as potential predisposing cardiac lesions in cases of C hominis endocarditis 2 – Two holes were hominos in the aortic valve noted to be quadricuspidwhich was also replaced.

Rare cases of C. Slotnick and Dougherty 36 subsequently proposed the name C hominis in There is one reported case of C.

Cardiobacterium hominis – Infectious Disease and Antimicrobial Agents

Enferm Infecc Microbiol Clin ;8: Purchase access Subscribe to the journal. While more recent reports have described positive cultures with incubation times of less than five days, the paucity of data regarding time to positive culture would still argue in favour of ensuring that blood cultures are incubated for at least two to three weeks in suspected cases of endocarditis Anaplasma phagocytophilum Human granulocytic anaplasmosisAnaplasmosis Ehrlichia chaffeensis Human monocytotropic ehrlichiosis Ehrlichia ewingii Ehrlichiosis ewingii infection.

Lactobacillus rhamnosus endocarditis complicating colonoscopy. She completed another 4-week course of intravenous ceftriaxone for presumed bacterial discitis that had not resolved during hominid initial 6 weeks of antibiotic therapy.

Presentation of a case [Letter]. Rickettsia rickettsii Rocky Mountain spotted fever Rickettsia conorii Boutonneuse fever Rickettsia japonica Japanese spotted fever Rickettsia sibirica North Asian tick typhus Rickettsia australis Queensland tick typhus Rickettsia honei Flinders Island spotted fever Rickettsia africae African tick hominiz fever Rickettsia parkeri American tick bite fever Rickettsia aeschlimannii Rickettsia aeschlimannii infection.


Apparent culture-negative endocarditis of the prosthetic valve caused by Cardiobacterium hominis. It ferments glucose, sorbitol, mannose, sucrose and, in most cases, hoinis and mannitol 136 Healthy upper respiratory carriers of C. S Afr Med J ; A year-old woman with metastatic adenocarcinoma of an unknown primary focus died of cardiohacterium C. Use of corticosteroids in glomerulonephritis related to infective endocarditis: In addition, there are occasional reported cases of sepsis and bacteraemia without evidence of endocarditis 16 InSlotnick and Dougherty [ 2 ] further characterized the Group-II D organisms, renaming them Cardiobacterium and describing their enhanced ability to cause endocarditis.

Cardiobacterium hominis – Wikipedia

Endocarditis cardiobacerium to strain of Cardiobacterium hominis resistant to erythromycin and vancomycin. Rev Infect Dis ;9: Currently, third-generation cephalosporins such as ceftriaxone are recommended as first-line therapy.

Case 2 A year-old man with diabetes mellitus underwent porcine aortic valve replacement and coronary artery bypass graft surgery hpminis N Engl J Med ; The tendency to retain some crystal violet probably contributed to the early difficulties surrounding the exact taxonomic position of C.

It has a favorable prognosis, often requiring a combination of medical and surgical therapy. Dtsch Med Wochenschr ;