El tratamiento farmacológico hipolipemiante con estatinas debería ser el más indicado en los individuos con Institut Català de Farmacologia. REVISIONES. Interacciones medicamentosas de agentes hipolipemiantes: aproximación para establecer y valorar su relevancia clínica. Revisión estructurada. As estatinas são agentes hipolipemiantes que exercem os seus efeitos através da inibição da HMG-CoA redutase, enzima fundamental na síntese do colesterol .

Author: Zulkikinos Nekus
Country: Qatar
Language: English (Spanish)
Genre: Science
Published (Last): 28 July 2007
Pages: 363
PDF File Size: 12.82 Mb
ePub File Size: 2.63 Mb
ISBN: 758-4-50390-244-6
Downloads: 6916
Price: Free* [*Free Regsitration Required]
Uploader: Vijora

Fenofibrate and warfarin interaction. Effect of gemfibrozil on the pharmacokinetics of pioglitazone.

Pleiotropic effects of statins: Statins inhibit HIV-1 infection by down-regulating Rho activity. Expert Opin Investig Drugs. Rhabdomyolysis with concurrent atorvastatin and diltiazem. Rhabdomyolysis due to a combination of itraconazole and simvastatin.

Negredo E, Rey-Joly yC. Interaction between enfuvirtide, an injectable fusion inhibitor, and niacin in an HIV-infected patient.

farmaco efeitos adversos dos hipolipemiantes

The effect of gemfibrozil on repaglinide pharmacokinetics persists for at least 12 h after the dose: Drug interactions; Rhabdomyolisis; Hypolipidemic drugs. Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of glimepiride. J R Coll Physicians Edinb.


Publicly accessible Penn Dissertations. J Natl Med Assoc. Clin Pharmacol Ther ; Efecto que no se observa para la pravastatina J Pharmacol Exp Ther. Basic Clin Pharmacol Toxicol. Curr Med Res Opin.

Focus on clinical and pharmacokinetics and drug interactions. Duration of fatmacologia of grapefruit juice on the pharmacokinetics of the CYP3A4 substrate simvastatin. A case report of acute neuromyopathy induced by concomitant use of colchicine and bezafibrate.

Rhabdomyolysis induced by rosuvastatin and sildenafil. The information was completed with those articles considered to be relevant. Interaction between fenofibrate and warfarin. Effects of gemfibrozil, itraconazole, and their combination on the pharmacokinetics and pharmacodynamics of repaglinide: Rhabdomyolysis with concurrent atorvastatina and diltiazem.

Fármacos Hipolipemiantes

Reduced efficacy of rosuvastatin by St. Non-concurrent dosing attenuates the pharmacokinetic interaction between amlodipine and simvastatin. Recently, many pleiotropic effects have been fadmacologia with these drugs, such as anti-inflammatory properties, improvement in endothelial function and benefits on hemostasis. Plasma concentration profiles of simvastatin 3-hydroxymethylglutaryl-coenzyme A reductase inhibitory activity in kidney transplant recipients with and without ciclosporin.


Pharmacokinetics of statins

Not all statins interfere with clopidogrel during antiplatelet therapy. Gemfibrozil increases plasma pravastatin concentrations and reduces pravastatin renal clearance. Presumed interaction of fusidic acid with simvastatin.

Different effects of itraconazole on the pharmacokinetics of fluvastatin and lovastatin. Pharmacodynamic and pharmacokinetic interaction between fenofibrate and farmacollogia. Franco 1,4Y. Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: Effects of grapefruit juice on the pharmacokinetics of pitavastatin and atorvastatin.